Representative of the World Health Organization, Ahmed Shadoul, said the organization needs $60 million in order to continue its activities in Yemen.
The sum is required urgently as it will be spent on the organization's life-saving response in all Yemeni areas this year, the Saba news agency quoted him as saying.
Yemen is facing outbreaks because of the acute shortages of supplies and other challenges such as power outages that forced water wells to shut down, he said.
"The shortage of foodstuffs has pushed the prices up. Families can't afford buying food and, because of this, malnutrition among children is now growing," he added.
The organization has delivered around 30 tons of medicines and health equipment to Yemen hospitals, he said, while urging donors to support it so that it can reach as many Yemenis as it can.
Recently, the organization said that around 9 million Yemeni people are in need of urgent medical help as many hospitals shut down due to lack of medicines and fuels as well as expanding conflict.
The blockade on all Yemeni sea, land and air routes were to blame for the shortages of supplies.
It was part of an Arab military intervention by the Saudi-led coalition.
Aid organizations are also facing huge challenges in conflict cities staff deaths have forced key agencies to suspend activities in the country.